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Article

Hepatocyte mARC1 promotes fatty liver disease

2 Feb 2023

Abstract excerpt

Background & Aims Non-alcoholic fatty liver disease (NAFLD) has a prevalence of ∼25% worldwide, with significant public health consequences yet few effective treatments. Human genetics can help elucidate novel biology and identify targets for new therapeutics. Genetic variants in mitochondrial amidoxime-reducing component 1 ( MTARC1 ) have been associated with NAFLD and liver-related mortality; however, its...

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PMID: 37122688
DOI: 10.1016/j.jhepr.2023.100693

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