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Article

Sphingosine 1-Phosphate Activates S1PR3 to Induce a Proinflammatory Phenotype in Human Myometrial Cells.

Endocrinology - 17 Apr 2023

Saurabh Kumar, Mbadhi Magdaleena Naemi, Prifti Kevin K, Martin Kaci T, Frolova Antonina I

Abstract excerpt

One of the common mechanisms responsible for obstetric complications, affecting millions of women every year, is abnormal uterine contractility. Despite the critical importance of this process for women's health, the mechanisms of uterine contraction regulation remain poorly understood. The initiation of uterine smooth muscle (myometrial) contraction is an inflammatory process, accompanied by upregulation of...

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Identifiers

PMID: 37120767
DOI: 10.1210/endocr/bqad066
PMCID: PMC10201982

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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