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Platelet-derived factors dysregulate placental sphingosine-1-phosphate receptor 2 in human trophoblasts

16 Apr 2023

Abstract excerpt

RESEARCH QUESTION: Sphingosine-1-phosphate (S1P) is an essential and bioactive sphingolipid with various functions, which acts through five different G-protein-coupled receptors (S1PR1-5). What is the localization of S1PR1-S1PR3 in the human placenta and what is the effect of different flow rates, various oxygen concentrations and platelet-derived factors on the expression profile of S1PR in trophoblasts? DESIGN:...

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PMID: 37301709
DOI: 10.1016/j.rbmo.2023.04.006

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