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Modeling hormonal and inflammatory contributions to preterm and term labor using uterine temporal transcriptomics

10 Jun 2016

Abstract excerpt

BACKGROUND: Preterm birth is now recognized as the primary cause of infant mortality worldwide. Interplay between hormonal and inflammatory signaling in the uterus modulates the onset of contractions; however, the relative contribution of each remains unclear. In this study we aimed to characterize temporal transcriptome changes in the uterus preceding term labor and preterm labor (PTL) induced by progesterone...

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PMID: 27291689
DOI: 10.1186/s12916-016-0632-4

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