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Article

IL-27 Mediates Pro-Inflammatory Effects via the ERK Signaling Pathway During Preterm Labor

8 Oct 2021

Abstract excerpt

Preterm labor (PTL) is a multifactorial syndrome that results in birth prior to 37 weeks of gestation. However, the specific molecular mechanisms underlying this condition have yet to be elucidated. Previous research demonstrated that the abnormal expression of IL-27, and its receptors, played a role in the pathophysiology of preterm labor. In the present study, we established a Lipopolysaccharide...

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PMID: 34691022
DOI: 10.3389/fimmu.2021.709229

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