Article
VEXAS: is it time to reshape the nosology of clonal hematopoiesis?
Expert review of hematology - 1 Jan 2000
Sujobert Pierre, Largeaud Laetitia, Jamilloux Yvan, Heiblig Maël, Kosmider Olivier
Abstract excerpt
INTRODUCTION: The recent description of VEXAS (for vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) challenges the nosological framework of myelodysplastic syndromes. AREAS COVERED: Clonal expansion driven by somatic mutations in cancer genes has been largely described in healthy aging individuals. Regarding hematopoiesis, the prevalence of clonal hematopoiesis has blurred the line between normal and...
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