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Article

Morphologic Deciphering of Hematopoietic Cell Vacuolization: Lessons From VEXAS Syndrome and Other Etiologies.

International journal of laboratory hematology - 1 Jun 2026

Abro Brooj, Deeb George, Asakrah Saja

Abstract excerpt

Vacuoles in hematopoietic cell precursors have garnered significant attention in recent years due to their association with a newly characterized clonal hematopoiesis with acquired mutations of ubiquitin like modifier activating enzyme 1 (ubiquitin-activating enzyme E1, UBA1) gene associated with clinical systemic autoinflammatory manifestations, known as VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41493425
DOI: 10.1111/ijlh.70056

Genes

UBA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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