Sex hormones and risk of epilepsy: A bidirectional Mendelian randomization study

Abstract excerpt

Background Multiple evidence has suggested complex interaction between sex hormones and epilepsy. However, whether there exists a causal association and the effect direction remains controversial. Here we aimed to examine the causative role of hormones in the risk of epilepsy and vice versa. Methods We conducted a bidirectional two-sample Mendelian randomization analysis using summary statistics from genome-wide...

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