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Article

Causal relationship between sleep traits and risk of Epilepsy: A Mendelian randomization study.

Epilepsy & behavior : E&B - 1 Apr 2025

Li Kaiji, Li Haonan, Wang Jinchao, Chen Xin, Li Lei, Wang Cong, Zhang Shu, Zhang Jianning

Abstract excerpt

BACKGROUND: Observational studies have identified a strong correlation between epilepsy and sleep traits, highlighting their interactive relationship. However, no studies have specifically examined the associations between sleep traits and epilepsy. In this context, we conducted a Mendelian Randomization (MR) investigation to explore the causal nature of these associations. METHODS: We performed a two-sample...

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Topics

Humans
Epilepsy
Mendelian Randomization Analysis
Sleep
Polymorphism, Single Nucleotide
Circadian Rhythm

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 39999664
DOI: 10.1016/j.yebeh.2025.110310

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