Article
Causal Relationships Between Epilepsy, Anti-Epileptic Drugs, and Serum Vitamin D and Vitamin D Binding Protein: A Bidirectional and Drug Target Mendelian Randomization Study.
CNS neuroscience & therapeutics - 1 Dec 2024
Cheng Zizhang, Zuo Jinyi, Peng Xintao, Zhang Haoran, Su Wenlong, Luan Guoming, Guan Yuguang
Abstract excerpt
AIMS: Previous studies suggest potential associations between epilepsy, anti-epileptic drugs (AEDs), and levels of vitamin D and vitamin D-binding protein (VDBP). This study aims to investigate the causal relationships among these variables using Mendelian Randomization (MR) methods. METHODS: Using summary data from genome-wide association studies on serum 25-hydroxyvitamin D [25(OH)D] levels (N = 417,580), VDBP...
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