Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence of Association between CTLA-4 Gene Polymorphisms and Colorectal Cancers in Saudi Patients.

Genes - 6 Apr 2023

Al-Harbi Nouf, Abdulla Maha-Hamadien, Vaali-Mohammed Mansoor-Ali, Bin Traiki Thamer, Alswayyed Mohammed, Al-Obeed Omar, Abid Islem, Al-Omar Suliman, Mansour Lamjed

Abstract excerpt

Cytotoxic T lymphocyte antigen-4 (CTLA-4) has been identified as an immunosuppressive molecule involved in the negative regulation of T cells. It is highly expressed in several types of autoimmune diseases and cancers including colorectal cancer (CRC). (1) Objective: To explore the association between CTLA-4 single nucleotide polymorphisms (SNP) and risk to (CRC) in the Saudi population. (2) Methods: In this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to CTLA-4 Antigen

Share to Diabetes and associated disorders

Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

Share to Saudi Arabia

Source

Open in PubMed Open full text

Identifiers

PMID: 37107632
DOI: 10.3390/genes14040874
PMCID: PMC10138150

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence of Association between CTLA-4 Gene Polymorphisms and Colorectal Cancers in Saudi Patients.PMID 37107632Read ↗

CTLA4 tagging polymorphisms and risk of colorectal cancer: a case–control study involving 2,306 subjectsSemantic proximity Read ↗

Association of cytotoxic T-lymphocyte antigen 4 rs231775 gene polymorphism with colorectal cancer risk.Semantic proximity Read ↗

Rs10204525 Polymorphism of the Programmed Death (PD-1) Gene Is Associated with Increased Risk in a Saudi Arabian Population with Colorectal Cancer.Semantic proximity Read ↗

CTLA-4 +49A>G polymorphism is associated with the risk but not with the progression of colorectal cancer in Chinese.Semantic proximity Read ↗

The association of CTLA-4 A49G polymorphism with colorectal cancer risk in a Chinese Han population.Semantic proximity Read ↗

Association of CTLA-4 variants with susceptibility to inflammatory bowel disease: a meta-analysis.Semantic proximity Read ↗

Association between the Cytotoxic T-lymphocyte antigen 4 +49G > A polymorphism and cancer risk: a meta-analysis.Semantic proximity Read ↗

Single nucleotide variants associated with colorectal cancer among Saudi patients: A systematic review.Semantic proximity Read ↗

Correlation between genetic polymorphisms within IL-1B and TLR4 genes and cancer risk in a Russian population: a case-control study.Semantic proximity Read ↗

Association between CTLA-4 60G/A and -1661A/G polymorphisms and the risk of cancers: a meta-analysis.Semantic proximity Read ↗

Association of interleukin-17A polymorphisms with the risk of colorectal cancer: A case-control study.Semantic proximity Read ↗

Investigation of CTLA-4 and CD28 gene polymorphisms in a group of Turkish patients with colorectal cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.