Article
CTLA4 tagging polymorphisms and risk of colorectal cancer: a case–control study involving 2,306 subjects
1 Aug 2018
Abstract excerpt
Background: CTLA4 is a candidate gene which has been implicated in the development of colorectal cancer (CRC). Patients and Methods: To determine the important role of CTLA-4 polymorphisms on risk of CRC, we genotyped four CTLA-4 tagging polymorphisms and calculated crude/adjusted ORs with their 95% CIs. We recruited 1,003 sporadic CRC cases and 1,303 controls. Results: The findings suggested that CTLA-4 rs231775...
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