Article
Association of interleukin-17A polymorphisms with the risk of colorectal cancer: A case-control study.
Cytokine - 1 Oct 2018
Bedoui Sinda A, Barbirou Mouadh, Stayoussef Mouna, Dallel Meriem, Mokrani Amina, Makni Lamia, Mezlini Amel, Bouhaouala Balkiss, Yacoubi-Loueslati Besma, Almawi Wassim Y
Abstract excerpt
BACKGROUND: Interleukin (IL)-17A is proinflammatory cytokine produced by Th17 cells, which play key, but sometimes inconsistent role in autoimmunity and cancer. Polymorphic variants in IL-17A gene were differentially associated with susceptibility to cancer, including colorectal cancer (CRC). AIM: We investigated the association between six IL-17A gene variants (rs3819024, rs2275913, rs3819025, rs10484879,...
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