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Article

Association between the Cytotoxic T-lymphocyte antigen 4 +49G > A polymorphism and cancer risk: a meta-analysis.

BMC cancer - 4 Oct 2010

Zheng Jian, Yu Xiao, Jiang Lan, Xiao Mang, Bai Bing, Lu Jiachun, Zhou Yifeng

Abstract excerpt

BACKGROUND: As a key gene in the immunosurveillance of cell malignancy, Cytotoxic T-lymphocyte antigen 4 (CTLA-4 is an important negative regulator of T cell activation and proliferation. The CTLA-4 +49G > A polymorphism is one of the most commonly studied polymorphisms in this gene due to its association with cancer risks, but previous results have been conflicting. METHODS: We preformed a meta-analysis using 22...

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Identifiers

PMID: 20920330
DOI: 10.1186/1471-2407-10-522
PMCID: PMC2958938

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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