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Article

Mapping Genetic Susceptibility to Stenosis in the Proximal Airway.

The Laryngoscope - 1 Nov 2023

Sharif Kayvon, Tierney William S, Davis Ruth J, Wohler Elizabeth, Sobreira Nara, Hillel Alexander T, Collins Samuel, Ramirez-Solano Marisol, Sheng Quanhu, Gelbard Alexander

Abstract excerpt

OBJECTIVES: Recent translational scientific efforts in subglottic stenosis (SGS) support a disease model where epithelial alterations facilitate microbiome displacement, dysregulated immune activation, and localized fibrosis. Yet despite recent advances, the genetic basis of SGS remains poorly understood. We sought to identify candidate risk genes associated with an SGS phenotype, investigate their biological...

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Share to Congenital Ear and Nasal Anomalies
Share to Constriction, Pathologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelial Cells

Share to Fibrosis

Share to Genetic Predisposition to Disease

Share to Tracheal and airway disorders

Share to Voice and Speech Disorders

Source

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Identifiers

PMID: 37102306
DOI: 10.1002/lary.30718
PMCID: PMC10593092

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