Article
Human Leukocyte Antigen Genotyping of Idiopathic Subglottic Stenosis.
The Laryngoscope - 1 Oct 2023
Rohlfing Matthew L, Hillel Alexander T, Wohler Elizabeth, Sobreira Nara, Phillips Elizabeth J, Mallal Simon A, Gelbard Alexander
Abstract excerpt
OBJECTIVE: Despite recent scientific inquiry, idiopathic subglottic stenosis (iSGS) remains an enigmatic disease. The consistent demographics of the affected population suggest genetic factors may contribute to disease susceptibility. Given the inflammation observed in the affected proximal airway mucosa, we interrogated disease association with human leukocyte antigen (HLA) polymorphisms. Polymorphisms in the...
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