Article

Idiopathic subglottic stenosis arises at the interface of host and pathogen

2022-02-04

Abstract excerpt

<h4>ABSTRACT</h4> Idiopathic subglottic stenosis (iSGS) is a rare fibrotic disease of the proximal airway affecting adult Caucasian women nearly exclusively. Life-threatening ventilatory obstruction occurs secondary to pernicious subglottic mucosal scar. Diverse diseases in divergent organ systems are associated with fibrosis, suggesting common biologic mechanisms. One well characterized pathway is chronic inflamm...

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Literature Corpus work: 8f94c112-12c7-527a-ac31-4fb4e0f32222
DOI: 10.1101/2022.02.02.22270308

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