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Article

Pharmacogenetics of tenofovir clearance among Southern Africans living with HIV

6 Mar 2023

Abstract excerpt

BACKGROUND: Tenofovir is a component of preferred combination antiretroviral therapy (ART) regimens in Africa. Few pharmacogenetic studies have been conducted on tenofovir exposure in Africa, where genetic diversity is greatest. OBJECTIVE: We characterized the pharmacogenetics of plasma tenofovir clearance in Southern Africans receiving tenofovir disoproxil fumarate (TDF) or tenofovir alafenamide (TAF). METHODS:...

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PMID: 37098852
DOI: 10.1097/fpc.0000000000000495

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