Article
Genomically matched therapy in refractory colorectal cancer according to ESMO Scale for Clinical Actionability of Molecular Targets: experience of a comprehensive cancer centre network.
Molecular oncology - 1 Sept 2023
Mulet Margalef Núria, Castillo Carmen, Mosteiro Miguel, Pérez Xavier, Aguilar Susana, Ruíz-Pace Fiorella, Gil Marta, Cuadra Carmen, Ruffinelli José Carlos, Martínez Mercedes, Losa Ferran, Soler Gema, Teulé Àlex, Castany Roser, Gallego Rosa, Ruíz Andrea, Garralda Elena, Élez Elena, Vivancos Ana, Tabernero Josep, Salazar Ramon, Dienstmann Rodrigo, Santos Vivas Cristina
Abstract excerpt
Efficiency of expanded genomic profiling (EGP) programmes in terms of final inclusion of patients in genomically matched therapies is still unknown. Fit patients with advanced and refractory colorectal cancer (CRC) were selected for an EGP programme. Next-generation sequencing (NGS) analysis from formalin-fixed paraffin-embedded tumour samples was performed. The purpose was to describe the prevalence of genomic...
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