Current practice of genomic profiling of patients with advanced solid tumours in Italy: the Italian Register of Actionable Mutations (RATIONAL) study.

doi:10.1016/j.ejca.2023.03.027

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Article

Current practice of genomic profiling of patients with advanced solid tumours in Italy: the Italian Register of Actionable Mutations (RATIONAL) study.

European journal of cancer (Oxford, England : 1990) - 1 Jul 2023

Normanno Nicola, De Luca Antonella, Abate Riziero Esposito, Morabito Alessandro, Milella Michele, Tabbò Fabrizio, Curigliano Giuseppe, Masini Cristina, Marchetti Paolo, Pruneri Giancarlo, Guarneri Valentina, Frassineti Giovanni L, Fasola Gianpiero, Adamo Vincenzo, Daniele Bruno, Berardi Rossana, Feroce Florinda, Maiello Evaristo, Pinto Carmine

Abstract excerpt

BACKGROUND: The Italian Register of Actionable Mutations (RATIONAL) is a multicentric, observational study collecting next-generation sequencing (NGS)-based tumour profiling data of patients with advanced solid tumours. METHODS: The study enrols patients who had available an NGS-based tumour profiling (Pathway-A) or undergo comprehensive genomic profiling (CGP) with FoundationOne CDx assays within the trial...

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PMID: 37167765
DOI: 10.1016/j.ejca.2023.03.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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