Article
Mutation of S461, in the GOLGA3 phosphorylation site, does not affect mouse spermatogenesis.
PeerJ - 1 Jan 2023
Xu Changtong, Zhu Mingcong, Zhao Shuqin, Zhang Xin, Wang Ying, Liu Mingxi
Abstract excerpt
Background: Golgin subfamily A member 3 (Golga3), a member of the golgin subfamily A, is highly expressed in mouse testis. The GOLGA3 protein, which contains eight phosphorylation sites, is involved in protein transport, cell apoptosis, Golgi localization, and spermatogenesis. Although it has been previously reported that nonsense mutations in Golga3 cause multiple defects in spermatogenesis, the role of Golga3...
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