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Article

Abnormal fertility, acrosome formation, IFT20 expression and localization in conditional Gmap210 knockout mice.

American journal of physiology. Cell physiology - 1 Jan 2020

Wang Zhenyu, Shi Yuqin, Ma Suheng, Huang Qian, Yap Yi Tian, Shi Lin, Zhang Shiyang, Zhou Ting, Li Wei, Hu Bo, Zhang Ling, Krawetz Stephen A, Pazour Gregory J, Hess Rex A, Zhang Zhibing

Abstract excerpt

GMAP210 (TRIP11) is a cis-Golgi network-associated protein and a Golgi membrane receptor for IFT20, an intraflagellar transport component essential for male fertility and spermiogenesis in mice. To investigate the role of GMAP210 in male fertility and spermatogenesis, floxed Gmap210 mice were bred with Stra8-iCre mice so that the Gmap210 gene is disrupted in spermatocytes and spermatids in this study. The...

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Source

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Identifiers

PMID: 31577511
DOI: 10.1152/ajpcell.00517.2018
PMCID: PMC6985835

Genes

IFT20
TRIP11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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