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Article

Teaching an old dog new tricks: A new tool for protein tyrosine phosphatase substrate discovery.

The Journal of biological chemistry - 1 May 2023

Bennett Anton M

Abstract excerpt

The identification of substrates for protein tyrosine phosphatases (PTPs) is critical for a complete understanding of how these enzymes function. In a recent study in the JBC, Bonham et al. developed a modified method combining substrate-trapping mutations with proximity-labeling MS to identify the protein substrates and interactors of PTP1B. This method revealed interaction networks in breast cancer cell models...

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Share to Protein Tyrosine Phosphatase, Non-Receptor Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37080392
DOI: 10.1016/j.jbc.2023.104731
PMCID: PMC10193000

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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