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Gene dysregulation in acute HIV-1 infection – early transcriptomic analysis reveals the crucial biological functions affected

3 Apr 2023

Abstract excerpt

Introduction: Transcriptomic analyses from early human immunodeficiency virus (HIV) infection have the potential to reveal how HIV causes widespread and lasting damage to biological functions, especially in the immune system. Previous studies have been limited by difficulties in obtaining early specimens. Methods: A hospital symptom-based screening approach was applied in a rural Mozambican setting to enrol...

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PMID: 37077524
DOI: 10.3389/fcimb.2023.1074847

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