Article
Functional genomic relationships in HIV-1 disease revealed by gene-expression profiling of primary human peripheral blood mononuclear cells.
The Journal of infectious diseases - 15 Jun 2005
Ockenhouse Christian F, Bernstein Wendy B, Wang Zhining, Vahey Maryanne T
Abstract excerpt
BACKGROUND: An assessment of biomarkers from an analysis of human peripheral blood mononuclear cell gene-expression profiles was made, to acquire an understanding of transcriptional changes associated with human immunodeficiency virus type 1 (HIV-1) infection in vivo. METHODS: Supervised learning algorithms were used to create signature gene sets that could be used to distinguish seropositive from seronegative...
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