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Article

Quantitative 1H Nuclear Magnetic Resonance Assay for the Rapid Detection of Pyrazinamide Resistance in Mycobacterium tuberculosis from Sputum Samples.

Journal of clinical microbiology - 23 May 2023

Lopez Juan M, Zimic Mirko, Vallejos Katherine, Sevilla Diego, Quispe-Carbajal Mariella, Roncal Elisa, Rodríguez Joseline, Rodríguez Jhojailith, Antiparra Ricardo, Arteaga Héctor, Gilman Robert H, Maruenda Helena, Sheen Patricia

Abstract excerpt

Tuberculosis (TB), caused by Mycobacterium tuberculosis, is one of the 10 leading killer diseases in the world. At least one-quarter of the population has been infected, and there are 1.3 million deaths annually. The emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains challenges TB treatments. One of the drugs widely used in first- and second-line regimens is pyrazinamide (PZA)....

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Identifiers

PMID: 37071032
DOI: 10.1128/jcm.01522-22
PMCID: PMC10204627

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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