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Transplanted human intestinal organoids: a resource for modeling human intestinal development

18 Apr 2023

Abstract excerpt

The in vitro differentiation of pluripotent stem cells into human intestinal organoids (HIOs) has served as a powerful means for creating complex three-dimensional intestinal structures. Owing to their diverse cell populations, transplantation into an animal host is supported with this system and allows the temporal formation of fully laminated structures, including crypt-villus architecture and smooth muscle...

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PMID: 37070767
DOI: 10.1242/dev.201416

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