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Gastrointestinal organoids: a next-generation tool for modeling human development

13 Jul 2020

Abstract excerpt

Gastrointestinal organoids are an exciting new tool for modeling human development, physiology, and disease in human tissue. Derived from pluripotent stem cells, gastrointestinal organoids consist of epithelial and mesenchymal cells organized in an intricate, three-dimensional structure that recapitulates the physiology and microscopic anatomy of the human gastrointestinal (GI) tract. In vitro derivation of...

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PMID: 32658619
DOI: 10.1152/ajpgi.00199.2020

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