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NF-kB and the CLL microenvironment

30 Mar 2023

Abstract excerpt

Chronic lymphocytic leukemia (CLL) is the most prevalent type of leukemia in the western world. Despite the positive clinical effects of new targeted therapies, CLL still remains an incurable and refractory disease and resistance to treatments are commonly encountered. The Nuclear Factor-Kappa B (NF-κB) transcription factor has been implicated in the pathology of CLL, with high levels of NF-κB associated with...

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PMID: 37064123
DOI: 10.3389/fonc.2023.1169397

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