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Article

Mechanisms of NF-κB deregulation in lymphoid malignancies.

Seminars in cancer biology - 1 Aug 2016

Krappmann Daniel, Vincendeau Michelle

Abstract excerpt

Deregulations promoting constitutive activation of canonical and non-canonical NF-κB signaling are a common feature of many lymphoid malignancies. Due to their cellular origin and the pivotal role of NF-κB for the normal function of B lymphocytes, B-cell malignancies are particularly prone to genetic aberrations that affect the pathway. Key positive regulators of NF-κB signaling can act as oncogenes that are...

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Identifiers

PMID: 27262792
DOI: 10.1016/j.semcancer.2016.05.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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