Article
Multiple polygenic scores improve bone mineral density prediction in an independent sample of Caucasian women.
Postgraduate medical journal - 1 Sept 2022
Xiao Xiangxue, Wu Qing
Abstract excerpt
PURPOSE OF THE STUDY: To determine if multiple Genetic Risk Scores (GRSs) improve bone mineral density (BMD) prediction over single GRS in an independent sample of Caucasian women. STUDY DESIGN: Based on summary statistics of four genome-wide association studies related to two osteoporosis-associated traits, namely BMD and heel quantitative ultrasound derived estimated BMD (eBMD), four GRSs were derived for 1205...
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