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Article

Common and rare variants in the exons and regulatory regions of osteoporosis-related genes improve osteoporotic fracture risk prediction.

The Journal of clinical endocrinology and metabolism - 1 Nov 2014

Lee Seung Hun, Kang Moo Il, Ahn Seong Hee, Lim Kyeong-Hye, Lee Gun Eui, Shin Eun-Soon, Lee Jong-Eun, Kim Beom-Jun, Cho Eun-Hee, Kim Sang-Wook, Kim Tae-Ho, Kim Hyun-Ju, Yoon Kun-Ho, Lee Won Chul, Kim Ghi Su, Koh Jung-Min, Kim Shin-Yoon

Abstract excerpt

CONTEXT: Osteoporotic fracture risk is highly heritable, but genome-wide association studies have explained only a small proportion of the heritability to date. Genetic data may improve prediction of fracture risk in osteopenic subjects and assist early intervention and management. OBJECTIVE: To detect common and rare variants in coding and regulatory regions related to osteoporosis-related traits, and to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25119311
DOI: 10.1210/jc.2014-1584

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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