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Article

Improved prediction of fracture risk leveraging a genome-wide polygenic risk score

3 Feb 2021

Abstract excerpt

BACKGROUND: Accurately quantifying the risk of osteoporotic fracture is important for directing appropriate clinical interventions. While skeletal measures such as heel quantitative speed of sound (SOS) and dual-energy X-ray absorptiometry bone mineral density are able to predict the risk of osteoporotic fracture, the utility of such measurements is subject to the availability of equipment and human resources....

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PMID: 33536041
DOI: 10.1186/s13073-021-00838-6

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