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Article

SNP rs17079281 decreases lung cancer risk through creating an YY1-binding site to suppress DCBLD1 expression.

Oncogene - 1 May 2020

Wang Yu, Ma Rongna, Liu Ben, Kong Jinyu, Lin Hongyan, Yu Xiao, Wang Ruoyang, Li Lei, Gao Ming, Zhou Baosen, Mohan Man, Yu Herbert, Hou Zhaoyuan, Shen Hongbin, Qian Biyun

Abstract excerpt

Genome-wide association studies (GWAS) have identified numerous genetic variants that are associated with lung cancer risk, but the biological mechanisms underlying these associations remain largely unknown. Here we investigated the functional relevance of a genetic region in 6q22.2 which was identified to be associated with lung cancer risk in our previous GWAS. We performed linkage disequilibrium (LD) analysis...

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Identifiers

PMID: 32231272
DOI: 10.1038/s41388-020-1278-4
PMCID: PMC7220863

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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