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Article

SMARCA4 Mutations in Carcinomas of the Esophagus, Esophagogastric Junction, and Stomach.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jun 2023

Neil Alexander J, Zhao Lei, Isidro Raymond A, Srivastava Amitabh, Cleary James M, Dong Fei

Abstract excerpt

Deficiency of SMARCA4, a member of the SWI/SNF chromatin remodeling complex, has been described in a subset of undifferentiated gastroesophageal carcinomas with an aggressive clinical course. The full spectrum and frequency of SMARCA4 mutations in gastroesophageal cancer are unknown. We interrogated our institutional database and identified patients with gastroesophageal carcinomas who underwent cancer...

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Identifiers

PMID: 37054973
DOI: 10.1016/j.modpat.2023.100183

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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