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A pan-cancer bioinformatic analysis of the carcinogenic role of SMARCA1 in human carcinomas

20 Sept 2022

Abstract excerpt

SMARCA1is a mammalian imitation switch (ISWI) gene that encodes for SNF2L. SNF2L is involved in regulating cell transition from a committed progenitor state to a differentiated state. Although many papers have detailed the correlation between SMARCA1 and different cancers, no pan-cancer analysis has been conducted to date. We started by exploring the potential carcinogenic role of SMARCA1 across 33 carcinomas...

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PMID: 36126083
DOI: 10.1371/journal.pone.0274823

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