Article
The clinicopathological and molecular analysis of gastric cancer with altered SMARCA4 expression.
Histopathology - 1 Aug 2020
Huang Shih-Chiang, Ng Kwai-Fong, Yeh Ta-Sen, Cheng Chi-Tung, Chen Min-Chi, Chao Yi-Chun, Chuang Huei-Chieh, Liu Yu-Jen, Chen Tse-Ching
Abstract excerpt
AIMS: In this study, we examine the clinicopathological and molecular features of gastric cancer (GC) with SMARCA4 alterations. METHODS AND RESULTS: We screened SMARCA4 alterations using immunohistochemistry on 1199 surgically resected GCs with information on Epstein-Barr virus (EBV), microsatellite instability (MSI) and other SWI/SNF subunits. SMARCA4, SMARCA2 and ARID1A mutations were investigated by targeted...
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