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Article

Repurposing antidiabetic drugs for rheumatoid arthritis: results from a two-sample Mendelian randomization study.

European journal of epidemiology - 1 Jul 2023

Qin Chenxi, Diaz-Gallo Lina-Marcela, Tang Bowen, Wang Yunzhang, Nguyen Thuy-Dung, Harder Arvid, Lu Yi, Padyukov Leonid, Askling Johan, Hägg Sara

Abstract excerpt

Despite increasing therapeutic options to treat rheumatoid arthritis (RA), many patients fail to reach treatment targets. The use of antidiabetic drugs like thiazolidinediones has been associated with lower RA risk. We aimed to explore the repurposing potential of antidiabetic drugs in RA prevention by assessing associations between genetic variation in antidiabetic drug target genes and RA using Mendelian...

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Identifiers

PMID: 37052755
DOI: 10.1007/s10654-023-01000-9
PMCID: PMC10276071

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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