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Article

Osteoarthritis and risk of type 2 diabetes: A two-sample Mendelian randomization analysis.

Journal of diabetes - 1 Nov 2023

Xing Xing, Wang Yining, Pan Faming, Cai Guoqi

Abstract excerpt

BACKGROUND: Physical inactivity is an independent risk factor for type 2 diabetes (T2D). Osteoarthritis (OA) is a common joint disease that limits patients' physical activity, which may increase risk of other chronic diseases including T2D. However, studies evaluating the effect of OA on T2D are scarce. This study aimed to investigate the causal effect of knee and hip OA on risk of T2D from a genetic perspective....

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Diabetes Mellitus, Type 2
Genome-Wide Association Study
Mendelian Randomization Analysis
Osteoarthritis, Hip
Osteoarthritis, Knee

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Osteoarthritis Treatment and Mechanisms

Polymorphism, Single Nucleotide

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Identifiers

PMID: 37525375
DOI: 10.1111/1753-0407.13451
PMCID: PMC10667649

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