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Rheumatoid arthritis and the risk of major cardiometabolic diseases: a Mendelian randomization study.

Scandinavian journal of rheumatology - 1 Jul 2023

Zhang K, Jia Y, Wang R, Guo D, Yang P, Sun L, Wang Y, Liu F, Zang Y, Shi M, Zhang Y, Zhu Z

Abstract excerpt

OBJECTIVE: Rheumatoid arthritis (RA) is suggested to be implicated in the development of cardiometabolic diseases. We conducted a Mendelian randomization (MR) study to assess potential causality for associations of RA with the risk of cardiometabolic diseases, including type 2 diabetes (T2D), coronary artery disease (CAD), and ischaemic stroke. METHOD: Seventy independent single-nucleotide polymorphisms (SNPs)...

Topics

Humans
Diabetes Mellitus, Type 2
Genome-Wide Association Study
Mendelian Randomization Analysis
Arthritis, Rheumatoid
Polymorphism, Single Nucleotide
Cardiovascular Diseases

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 35658786
DOI: 10.1080/03009742.2022.2070988

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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