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Article

The clonal heterogeneity of colon cancer with liver metastases.

Journal of gastroenterology - 1 Jul 2023

Chen Guanxuan, Zhu Wanqi, Liu Yang, Zhang Liwen, Xie Li, Song Xingguo, Song Xianrang

Abstract excerpt

BACKGROUND: Colon cancer with liver metastases (CCLM) characterized by genetic heterogeneity is an evolutionary process leading to variations in response to selective pressure, but the underlying evolutionary models still remains unclear. METHODS: Total of 30 samples, including primary tumor and two to four matched liver metastases from 8 treatment-naïve patients with CCLM were collected, and subjected to...

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Humans
Colonic Neoplasms
Liver Neoplasms
Genomics
Mutation

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 37042990
DOI: 10.1007/s00535-023-01989-6
PMCID: PMC10307713

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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