Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Accelerated Epigenetic Aging Is Associated With Multiple Cardiometabolic, Hematologic, and Renal Abnormalities: A Project Baseline Health Substudy

11 Apr 2023

Abstract excerpt

Background: Epigenetic clocks estimate chronologic age using methylation levels at specific loci. We tested the hypothesis that accelerated epigenetic aging is associated with abnormal values in a range of clinical, imaging, and laboratory characteristics. Methods: The Project Baseline Health Study recruited 2502 participants, including 1661 with epigenetic age estimates from the Horvath pan-tissue clock. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth, Development, and Health
Share to Epigenetics and DNA Methylation
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37039013
DOI: 10.1161/circgen.122.003772

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Accelerated Epigenetic Aging Is Associated With Multiple Cardiometabolic, Hematologic, and Renal Abnormalities: A Project Baseline Health SubstudyPMID 37039013Read ↗

Epigenetic age acceleration links atherogenic dyslipidaemia, inflammageing and frailty with adverse cardiovascular outcomes in older adults (UFO): a lipid-metabolome and epigenetic clock analysisSemantic proximity Read ↗

DNAm-based signatures of accelerated aging and mortality in blood are associated with low renal functionSemantic proximity Read ↗

The Sociodemographic and Lifestyle Correlates of Epigenetic Aging in a Nationally Representative U.S. Study of Younger AdultsSemantic proximity Read ↗

Systems Age: A single blood methylation test to quantify aging heterogeneity across 11 physiological systemsSemantic proximity Read ↗

Epigenetic Clocks: In Aging-Related and Complex DiseasesSemantic proximity Read ↗

The association of accelerated epigenetic age with all-cause mortality in cardiac catheterization patients as mediated by vascular and cardiometabolic outcomesSemantic proximity Read ↗

Associations Between Epigenetic Age Acceleration and microRNA Expression Among U.S. FirefightersSemantic proximity Read ↗

Association of Epigenetic Age Acceleration with Early Stage Heart Failure: Sex-Specific Effects in the Project Baseline Health StudySemantic proximity Read ↗

Multi-omic underpinnings of epigenetic aging and human longevity.Semantic proximity Read ↗

Associations of Body Composition and Physical Activity Level With Multiple Measures of Epigenetic Age AccelerationSemantic proximity Read ↗

A Novel Blood-Based Epigenetic Clock for Intrinsic Capacity Predicts Mortality and is Associated with Clinical, Immunological and Lifestyle FactorsSemantic proximity Read ↗

Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.