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Associations of Body Composition and Physical Activity Level With Multiple Measures of Epigenetic Age Acceleration

14 Nov 2020

Abstract excerpt

Epigenetic clocks use DNA methylation to estimate biological age. Whether body composition and physical activity are associated with these clocks is not well understood. Using blood samples collected at enrollment (2003-2009) from 2,758 women in the US nationwide Sister Study, we calculated 6 epigenetic age acceleration metrics using 4 epigenetic clocks (Hannum, Horvath, PhenoAge, GrimAge). Recreational physical...

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PMID: 33693587
DOI: 10.1093/aje/kwaa251

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