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Article

DNAm-based signatures of accelerated aging and mortality in blood are associated with low renal function

2 Jun 2021

Abstract excerpt

BACKGROUND: The difference between an individual's chronological and DNA methylation predicted age (DNAmAge), termed DNAmAge acceleration (DNAmAA), can capture life-long environmental exposures and age-related physiological changes reflected in methylation status. Several studies have linked DNAmAA to morbidity and mortality, yet its relationship with kidney function has not been assessed. We evaluated the...

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PMID: 34078457
DOI: 10.1186/s13148-021-01082-w

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