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Systems Age: A single blood methylation test to quantify aging heterogeneity across 11 physiological systems

2023-07-17

Abstract excerpt

Individuals, organs, tissues, and cells age in diverse ways throughout the lifespan. Epigenetic clocks attempt to quantify differential aging between individuals, but they typically summarize aging as a single measure, ignoring within-person heterogeneity. Our aim was to develop novel systems-based methylation clocks that, when assessed in blood, capture aging in distinct physiological systems. We combined supervi...

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Identifiers and source

Literature Corpus work
f84dfe75-8560-5f33-8b3a-75946f89dd45
DOI
10.1101/2023.07.13.548904
Open publication

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Systems Age: A single blood methylation test to quantify aging heterogeneity across 11 physiological systemsDOI 10.1101/2023.07.13.548904
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