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Associations Between Epigenetic Age Acceleration and microRNA Expression Among U.S. Firefighters

1 Jan 2023

Abstract excerpt

Epigenetic changes may be biomarkers of health. Epigenetic age acceleration (EAA), the discrepancy between epigenetic age measured via epigenetic clocks and chronological age, is associated with morbidity and mortality. However, the intersection of epigenetic clocks with microRNAs (miRNAs) and corresponding miRNA-based health implications have not been evaluated. We analyzed DNA methylation and miRNA profiles...

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PMID: 37953967
DOI: 10.1177/25168657231206301

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