Pharmacogenetics as Personalized Medicine: Association Investigation of SOD2 rs4880, CYP2C19 rs4244285, and FCGR2A rs1801274 Polymorphisms in a Breast Cancer Population in Iraqi Women.

doi:10.1016/j.clbc.2018.01.009

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Article

Pharmacogenetics as Personalized Medicine: Association Investigation of SOD2 rs4880, CYP2C19 rs4244285, and FCGR2A rs1801274 Polymorphisms in a Breast Cancer Population in Iraqi Women.

Clinical breast cancer - 1 Oct 2018

Jabir Ferdous A, Hoidy Wisam H

Abstract excerpt

BACKGROUND: Breast cancer is the most common cancer in women characterized by a high variable clinical outcome among individuals treated with targeted therapies. PATIENTS AND METHODS: In this study, we performed a population-based approach intersecting high-throughput genotype data from Iraqi populations with publicly available pharmacogenomics information to estimate the frequency of genotypes correlated with...

Topics

Adult
Asian People
Breast Neoplasms
Cyclophosphamide
Cytochrome P-450 CYP2C19
Doxorubicin
Female
Genetic Predisposition to Disease
Genotype
Humans
Iraq

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Odds Ratio

Pharmacogenetics

Polymorphism, Single Nucleotide

Precision Medicine

Receptors, IgG

Risk Factors

Source

Open in PubMed

Identifiers

PMID: 29482947
DOI: 10.1016/j.clbc.2018.01.009

Genes

SOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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