Simultaneous Expression of Chicken Granulocyte Monocyte Colony-Stimulating Factor and the Hemagglutinin-Neuraminidase Epitope of the Virulent Newcastle Disease Virus Genotype VII C22 Strain in a Functional Synthetic Recombinant Adenovirus as a Genotype-Matched Vaccine with Potential Antiviral Activity.

doi:10.1128/spectrum.04024-22

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Simultaneous Expression of Chicken Granulocyte Monocyte Colony-Stimulating Factor and the Hemagglutinin-Neuraminidase Epitope of the Virulent Newcastle Disease Virus Genotype VII C22 Strain in a Functional Synthetic Recombinant Adenovirus as a Genotype-Matched Vaccine with Potential Antiviral Activity.

Microbiology spectrum - 15 Jun 2023

Adam Fathalrhman Eisa Addoma, Zhao Xueliang, Guan Zhao, Chang Zhengwu, Thrusfield Michael, Lu Kejia, El Tigani-Asil El Tigani Ahmed, Terab Abdelnasir Mohammed Adam, Ismael Mohamedelfateh, Tong Lina, Prince-Theodore Daguia Wenam, Luo Chen, Xiao Sa, Wang Xinglong, Liu Haijin, Yang Zengqi

Abstract excerpt

When it comes to the prevention of clinical signs and mortality associated with infection of the Newcastle disease virus (NDV), vaccination has been very effective. However, recent evidence has proven that more highly virulent strains are emerging that bypass existing immune protection and pose a serious threat to the global poultry industry. Here, a novel rescued adenovirus 5-coexpressed chicken granulocyte...

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PMID: 37036344
DOI: 10.1128/spectrum.04024-22
PMCID: PMC10269747

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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Simultaneous Expression of Chicken Granulocyte Monocyte Colony-Stimulating Factor and the Hemagglutinin-Neuraminidase Epitope of the Virulent Newcastle Disease Virus Genotype VII C22 Strain in a Functional Synthetic Recombinant Adenovirus as a Genotype-Matched Vaccine with Potential Antiviral Activity.PMID 37036344Read ↗

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