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Article

Evaluation of the safety and protection efficacy of an attenuated genotype vii newcastle disease virus strain as a candidate vaccine.

Microbial pathogenesis - 1 Feb 2020

Xu Xiaohong, Li Jindou, Ding Jiaxin, Yang Mingxi, Xue Cong, Wang Jianzhong, Cong Yanlong, Yin Renfu, Qian Jing, Jin Ningyi, Ding Zhuang

Abstract excerpt

Newcastle disease (ND) is a serious avian infectious disease, causing severe economic loss worldwide. Its prevention depends on comprehensive vaccination scheme against Newcastle disease virus (NDV). However, current vaccine strains are of different genotypes with prevalent circulating strains (genotype VII), with significant genetic distance. Our team previously generated a genotype matched attenuated NDV strain...

Topics

Animals
Antibodies, Viral
Chickens
Genotype
Microbial Sensitivity Tests
Newcastle Disease
Newcastle disease virus
Poultry Diseases
Vaccination
Vaccines, Attenuated

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Viral Fusion Proteins

Viral Vaccines

Virus Shedding

Source

Identifiers

PMID: 31682996
DOI: 10.1016/j.micpath.2019.103831

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-31682996-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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