Article
Effects of MBOAT7 polymorphism and steatosis on liver function assessed by methacetin breath test.
European journal of clinical investigation - 1 Aug 2023
Di Ciaula Agostino, Bonfrate Leonilde, Shanmugam Harshitha, Weber Susanne N, Krawczyk Marcin, Portincasa Piero
Abstract excerpt
BACKGROUND: MBOAT7 rs641738 variant is a risk factor for nonalcoholic fatty liver disease (NAFLD) and liver fibrosis, but the relationship between this polymorphism and early liver dysfunction remains uncertain. METHODS: Eighty outpatients underwent blood analyses, liver imaging by ultrasound and acoustic radiation force impulse shear wave elastography and were genotyped for MBOAT7 (wild-type [WT], rs641738...
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